The recent increased rate of published information on the genetics of asthma suggests that the gene(s) for the clinical condition recognized as asthma could be established within several years. Although asthma is a very common disease, it has defied a clear genetic explanation. Older clinical studies of asthma and allergy in twins consistently showed that pairs of identical twins were more likely than pairs of nonidentical twins to have asthma or allergies. Statistical analysis of the twin data has supported a genetic cause for both asthma and allergies. Modern genetic techniques now allow precise evaluation of the causes of diseases that likely have a genetic background; however, a review of the clinical presentation of asthma and the results of the studies published to date indicates the difficulties encountered in the explanation of the genetics of this disease.
source: Russell Hopp, M.D. Genetics of Asthma.
source: Russell Hopp, M.D. Genetics of Asthma.
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